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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3nux3NVCyclin-dependent kinase 62.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3nux3NVCyclin-dependent kinase 62.7.11.221.000
4ez50RSCyclin-dependent kinase 62.7.11.220.529
2vv9IM9Cyclin-dependent kinase 22.7.11.220.510
4bcmT7ZCyclin-dependent kinase 22.7.11.220.510
2uzbC75Cyclin-dependent kinase 22.7.11.220.497
2w05FRTCyclin-dependent kinase 22.7.11.220.494
1fvv107Cyclin-dependent kinase 22.7.11.220.491
2w17I19Cyclin-dependent kinase 22.7.11.220.482
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.474
3ezvEZVCyclin-dependent kinase 22.7.11.220.467
4grb0XGCasein kinase II subunit alpha2.7.11.10.466
4dgmAGICasein kinase II subunit alpha2.7.11.10.464
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.461
3q9xEMOCasein kinase II subunit alpha2.7.11.10.460
5av2KMPDeath-associated protein kinase 12.7.11.10.460
3my5RFZCyclin-dependent kinase 22.7.11.220.457
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.453
4eooATPCyclin-dependent kinase 22.7.11.220.453
2pvmP29Casein kinase II subunit alpha2.7.11.10.451
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.451
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.449
3eb0DRKUncharacterized protein/0.448
3qxpX64Cyclin-dependent kinase 22.7.11.220.448
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.447
3nynSGVG protein-coupled receptor kinase 62.7.11.160.446
2ckeIQUDeath-associated protein kinase 2/0.445
3bqr4RBDeath-associated protein kinase 3/0.445
3mb714ICasein kinase II subunit alpha2.7.11.10.445
3nup3NUCyclin-dependent kinase 62.7.11.220.444
2fvdLIACyclin-dependent kinase 22.7.11.220.443
2vu3LZECyclin-dependent kinase 22.7.11.220.443
2pvlP55Casein kinase II subunit alpha2.7.11.10.442
3u4uLNHCasein kinase II subunit alpha2.7.11.10.442
3at4CCKCasein kinase II subunit alpha2.7.11.10.440