sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3jq9	AX1	Pteridine reductase, putative

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3jq9	AX1	Pteridine reductase, putative	/	1.000
2x9n	AX3	Pteridine reductase	/	0.611
3jqg	AX6	Pteridine reductase, putative	/	0.604
3jqb	DX6	Pteridine reductase, putative	/	0.600
2wd7	VGD	Pteridine reductase	/	0.597
3jq7	DX2	Pteridine reductase, putative	/	0.597
2yhu	WHF	Pteridine reductase	/	0.596
2x9g	LYA	Pteridine reductase	/	0.553
3bmc	FOL	Pteridine reductase	/	0.542
3bmn	AX3	Pteridine reductase	/	0.541
3mcv	MCV	Pteridine reductase	/	0.535
3bmo	NAP	Pteridine reductase	/	0.478
2x9v	TMQ	Pteridine reductase	/	0.463
3bmq	AX5	Pteridine reductase	/	0.459
3gn2	AX8	Pteridine reductase	/	0.446