sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3iqg | ASN_TRP_ASN_ILE | Cysteine synthase | 2.5.1.47 | 1.000 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.721 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.520 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.507 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.479 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.468 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.466 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.465 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.462 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.461 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.458 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.457 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.456 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.455 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.454 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.451 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.448 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.447 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.446 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.446 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.446 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.445 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.445 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.444 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.444 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.443 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.442 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.440 |