sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3bmc	FOL	Pteridine reductase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3bmc	FOL	Pteridine reductase	/	1.000
2wd7	VGD	Pteridine reductase	/	0.600
2x9n	AX3	Pteridine reductase	/	0.575
3mcv	MCV	Pteridine reductase	/	0.569
3jqg	AX6	Pteridine reductase, putative	/	0.564
3jq9	AX1	Pteridine reductase, putative	/	0.549
2yhu	WHF	Pteridine reductase	/	0.538
3jqb	DX6	Pteridine reductase, putative	/	0.528
2x9g	LYA	Pteridine reductase	/	0.526
3jq7	DX2	Pteridine reductase, putative	/	0.507
3bmo	NAP	Pteridine reductase	/	0.483
3bmn	AX3	Pteridine reductase	/	0.468
2vz0	D64	Pteridine reductase	/	0.443
3bmq	AX5	Pteridine reductase	/	0.441