sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2y53 | NAP | 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2y53 | NAP | 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase | / | 1.000 | |
| 2vro | NDP | 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase | / | 0.601 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.502 | |
| 3iwk | NAD | Aminoaldehyde dehydrogenase | / | 0.489 | |
| 4go2 | TAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.486 | |
| 4i9b | NAD | Putative betaine aldehyde dehyrogenase | / | 0.475 | |
| 1uxn | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.467 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.467 | |
| 3rhh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.465 | |
| 4zuk | NAD | Alpha-aminoadipic semialdehyde dehydrogenase | 1.2.1.31 | 0.460 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2eit | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.445 | |
| 4zz7 | NAD | Methylmalonate-semialdehyde dehydrogenase | / | 0.444 | |
| 2esd | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.443 |