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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vtrLZBCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2vtrLZBCyclin-dependent kinase 22.7.11.221.000
3lfqA28Cyclin-dependent kinase 22.7.11.220.611
2w1hL0FCyclin-dependent kinase 22.7.11.220.582
3le62BZCyclin-dependent kinase 22.7.11.220.573
2c6o4SPCyclin-dependent kinase 22.7.11.220.556
2ds11CDCyclin-dependent kinase 22.7.11.220.554
3r9dX6BCyclin-dependent kinase 22.7.11.220.535
2bheBRYCyclin-dependent kinase 22.7.11.220.532
3rk708ZCyclin-dependent kinase 22.7.11.220.531
2r64740Cyclin-dependent kinase 22.7.11.220.529
3lfnA27Cyclin-dependent kinase 22.7.11.220.526
2uznC96Cyclin-dependent kinase 22.7.11.220.525
4fks46KCyclin-dependent kinase 22.7.11.220.524
1ykr628Cyclin-dependent kinase 22.7.11.220.521
3qwjX6ACyclin-dependent kinase 22.7.11.220.520
1aq1STUCyclin-dependent kinase 22.7.11.220.516
2c6kDT2Cyclin-dependent kinase 22.7.11.220.516
2xmyCDKCyclin-dependent kinase 22.7.11.220.516
4fkv61KCyclin-dependent kinase 22.7.11.220.516
2a0cCK9Cyclin-dependent kinase 22.7.11.220.514
3qtxX43Cyclin-dependent kinase 22.7.11.220.513
1y91CT9Cyclin-dependent kinase 22.7.11.220.512
1pxlCK4Cyclin-dependent kinase 22.7.11.220.511
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.511
1oitHDTCyclin-dependent kinase 22.7.11.220.510
3rni21ZCyclin-dependent kinase 22.7.11.220.510
4fkt48KCyclin-dependent kinase 22.7.11.220.508
2uzoC62Cyclin-dependent kinase 22.7.11.220.506
1v1k3FPCyclin-dependent kinase 22.7.11.220.505
3r1yX76Cyclin-dependent kinase 22.7.11.220.504
2r3jSCJCyclin-dependent kinase 22.7.11.220.502
3rpo24ZCyclin-dependent kinase 22.7.11.220.497
1pxoCK7Cyclin-dependent kinase 22.7.11.220.493
3r7iX9ICyclin-dependent kinase 22.7.11.220.492
1pxmCK5Cyclin-dependent kinase 22.7.11.220.490
2b52D42Cyclin-dependent kinase 22.7.11.220.489
4acm7YGCyclin-dependent kinase 22.7.11.220.487
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.486
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.486
1g5sI17Cyclin-dependent kinase 22.7.11.220.485
4ek816KCyclin-dependent kinase 22.7.11.220.485
4fki09KCyclin-dependent kinase 22.7.11.220.482
3rk909ZCyclin-dependent kinase 22.7.11.220.480
2btrU73Cyclin-dependent kinase 22.7.11.220.479
3qzgX67Cyclin-dependent kinase 22.7.11.220.479
1gih1PUCyclin-dependent kinase 22.7.11.220.478
4erwSTUCyclin-dependent kinase 22.7.11.220.477
3iggEFQCyclin-dependent kinase 22.7.11.220.473
1hckATPCyclin-dependent kinase 22.7.11.220.472
2b53D23Cyclin-dependent kinase 22.7.11.220.472
2vv9IM9Cyclin-dependent kinase 22.7.11.220.472
2a4lRRCCyclin-dependent kinase 22.7.11.220.471
1oirHDYCyclin-dependent kinase 22.7.11.220.470
2duv371Cyclin-dependent kinase 22.7.11.220.466
3rjc06ZCyclin-dependent kinase 22.7.11.220.463
1y8yCT7Cyclin-dependent kinase 22.7.11.220.458
3lfsA07Cyclin-dependent kinase 22.7.11.220.455
3r71X86Cyclin-dependent kinase 22.7.11.220.453
4fkq42KCyclin-dependent kinase 22.7.11.220.453
1ke7LS3Cyclin-dependent kinase 22.7.11.220.450
3r7uX96Cyclin-dependent kinase 22.7.11.220.449
3rpv26ZCyclin-dependent kinase 22.7.11.220.449
2c6lDT4Cyclin-dependent kinase 22.7.11.220.444
1v0pPVBCell division control protein 2 homolog2.7.11.220.441
2vtqLZACyclin-dependent kinase 22.7.11.220.441
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.440