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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.682
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.645
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.632
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.631
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.630
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.624
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.617
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.608
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.605
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.605
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.605
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.603
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.598
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.596
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.595
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.594
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.593
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.592
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.588
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.588
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.586
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.580
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.576
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.569
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.569
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.565
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.565
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.561
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.561
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.560
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.558
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.554
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.548
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.547
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.545
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.537
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.537
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.537
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.534
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.530
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.527
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.526
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.520
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
4yxsEMUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.507
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.500
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.460
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.456
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.452
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
1jbpADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440