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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.705
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.612
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.610
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.606
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.572
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.571
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.570
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.567
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.558
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.557
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.556
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.544
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.544
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.526
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.526
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.523
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.520
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.507
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.502
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.492
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.463
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3cqwCQWRAC-alpha serine/threonine-protein kinase2.7.11.10.460
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
4yxsEMUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442