scPDB - Distribution of Cavity Similarity values of 2qzr entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29	1.000
1f3e	DPZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.622
2bbf	344	Queuine tRNA-ribosyltransferase	2.4.2.29	0.610
1efz	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.604
1q4w	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.603
1n2v	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.598
1k4h	APQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.589
4gg9	0WW	Queuine tRNA-ribosyltransferase	2.4.2.29	0.570
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.567
2z1x	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.565
1y5x	E89	Queuine tRNA-ribosyltransferase	2.4.2.29	0.563
1y5w	NEZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.557
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.554
1q63	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.545
2pot	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.544
2z1w	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.540
3gc5	2MQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.539
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.539
4fps	0UX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.535
3ge7	AFQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.533
4gcx	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.527
4hsh	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.525
4gi4	0EX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.520
1ozq	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.513
3gc4	AAQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.504
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29	0.500
3sm0	AEK	Queuine tRNA-ribosyltransferase	2.4.2.29	0.498
4giy	0WY	Queuine tRNA-ribosyltransferase	2.4.2.29	0.498
1q66	KMB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.492
4hqv	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.491
3bll	BPQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.478
4h7z	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.474
1pxg	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.473
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.472
1q65	BHB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.465
3qgf	46F	Genome polyprotein	2.7.7.48	0.465
4o9c	COA	Acetyl-CoA acetyltransferase	2.3.1.9	0.465
1c3x	8IG	Purine nucleoside phosphorylase	2.4.2.1	0.464
4hvx	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.464
5ero	210	Fusicoccadiene synthase	2.5.1.29	0.459
3rsv	3RS	Beta-secretase 1	3.4.23.46	0.452
3otw	COA	Phosphopantetheine adenylyltransferase	/	0.451
4fsa	0V3	Queuine tRNA-ribosyltransferase	2.4.2.29	0.451
1iol	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.450
2w3a	TOP	Dihydrofolate reductase	1.5.1.3	0.450
1f8g	NAD	NAD(P) transhydrogenase subunit alpha part 1	1.6.1.2	0.448
4h6z	ACO	Alpha-tubulin N-acetyltransferase 1	/	0.447
1h50	FMN	Pentaerythritol tetranitrate reductase	/	0.446
2a0y	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.444
3ime	BZ2	Pantothenate synthetase	6.3.2.1	0.444
3dyl	IBM	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.443
2ivn	ANP	tRNA N6-adenosine threonylcarbamoyltransferase	/	0.442
3b4y	F42	F420-dependent glucose-6-phosphate dehydrogenase	/	0.442
2jds	L20	cAMP-dependent protein kinase catalytic subunit alpha	2.7.11.11	0.441
3img	BZ3	Pantothenate synthetase	6.3.2.1	0.441
1q1r	FAD	Putidaredoxin reductase	1.18.1.5	0.440
2cf6	NAP	Cinnamyl alcohol dehydrogenase 5	1.1.1.195	0.440