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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2hu2NADC-terminal binding protein 1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2hu2NADC-terminal binding protein 1/1.000
1hkuNADC-terminal-binding protein 11.1.10.602
2omeNADC-terminal-binding protein 2/0.534
4lcjNADC-terminal-binding protein 2/0.509
1dgmADNAdenosine kinase2.7.1.200.482
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.465
4e5mNAPPhosphonate dehydrogenase1.20.1.10.460
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.460
2dbzNAPGlyoxylate reductase1.1.1.260.459
1il0NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.457
3gqvNAPEnoyl reductase LovC10.456
2c29NAPDihydroflavonol 4-reductase/0.455
2f3rG5PGuanylate kinase2.7.4.80.453
4rvgTYDD-mycarose 3-C-methyltransferase/0.450
4i1iNADMalate dehydrogenase/0.449
5d3qGDPDynamin-13.6.5.50.448
2ft9CHDFatty acid-binding protein 2, liver/0.447
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.447
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
3toxNAPPutative oxidoreductase/0.444
4dbzNDPPutative ketoacyl reductase1.3.10.444
2c3cFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.443
3in6FMNUncharacterized protein/0.443
1ae1NAPTropinone reductase 1/0.442
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.442
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.440
3p62FMNPentaerythritol tetranitrate reductase/0.440
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.440