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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2exmZIPCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2exmZIPCyclin-dependent kinase 22.7.11.221.000
1w8cN69Cyclin-dependent kinase 22.7.11.220.584
3r83Z14Cyclin-dependent kinase 22.7.11.220.582
4fklCK2Cyclin-dependent kinase 22.7.11.220.570
2a4lRRCCyclin-dependent kinase 22.7.11.220.553
3r8lZ30Cyclin-dependent kinase 22.7.11.220.533
3r7yZ04Cyclin-dependent kinase 22.7.11.220.531
2c6o4SPCyclin-dependent kinase 22.7.11.220.522
3r1yX76Cyclin-dependent kinase 22.7.11.220.519
2a0cCK9Cyclin-dependent kinase 22.7.11.220.516
1oitHDTCyclin-dependent kinase 22.7.11.220.515
3r8vZ62Cyclin-dependent kinase 22.7.11.220.503
3rahO1ZCyclin-dependent kinase 22.7.11.220.503
3qzgX67Cyclin-dependent kinase 22.7.11.220.502
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.501
4kd11QKCyclin-dependent kinase 22.7.11.220.501
4fkpLS5Cyclin-dependent kinase 22.7.11.220.499
1hckATPCyclin-dependent kinase 22.7.11.220.496
3raiX85Cyclin-dependent kinase 22.7.11.220.493
3qx2X63Cyclin-dependent kinase 22.7.11.220.492
3rpo24ZCyclin-dependent kinase 22.7.11.220.491
4fkq42KCyclin-dependent kinase 22.7.11.220.491
4ek610KCyclin-dependent kinase 22.7.11.220.490
4ek816KCyclin-dependent kinase 22.7.11.220.488
1e1xNW1Cyclin-dependent kinase 22.7.11.220.486
2btrU73Cyclin-dependent kinase 22.7.11.220.486
3lfqA28Cyclin-dependent kinase 22.7.11.220.486
2c6kDT2Cyclin-dependent kinase 22.7.11.220.485
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.485
3qwjX6ACyclin-dependent kinase 22.7.11.220.484
3qxoX65Cyclin-dependent kinase 22.7.11.220.484
1b38ATPCyclin-dependent kinase 22.7.11.220.483
1oirHDYCyclin-dependent kinase 22.7.11.220.483
4fkg4CKCyclin-dependent kinase 22.7.11.220.481
1pxoCK7Cyclin-dependent kinase 22.7.11.220.480
2r3iSCFCyclin-dependent kinase 22.7.11.220.479
3r7vZ02Cyclin-dependent kinase 22.7.11.220.479
1pxmCK5Cyclin-dependent kinase 22.7.11.220.478
4fkt48KCyclin-dependent kinase 22.7.11.220.476
1pxjCK2Cyclin-dependent kinase 22.7.11.220.475
1y8yCT7Cyclin-dependent kinase 22.7.11.220.473
2uzoC62Cyclin-dependent kinase 22.7.11.220.472
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.472
2vtsLZCCyclin-dependent kinase 22.7.11.220.472
3iggEFQCyclin-dependent kinase 22.7.11.220.472
3r71X86Cyclin-dependent kinase 22.7.11.220.472
3qqlX03Cyclin-dependent kinase 22.7.11.220.470
3lfnA27Cyclin-dependent kinase 22.7.11.220.466
3r7uX96Cyclin-dependent kinase 22.7.11.220.464
2r3fSC8Cyclin-dependent kinase 22.7.11.220.462
1h0w207Cyclin-dependent kinase 22.7.11.220.460
1ke5LS1Cyclin-dependent kinase 22.7.11.220.460
2vthLZ2Cyclin-dependent kinase 22.7.11.220.459
4erwSTUCyclin-dependent kinase 22.7.11.220.459
1ykr628Cyclin-dependent kinase 22.7.11.220.458
2r3jSCJCyclin-dependent kinase 22.7.11.220.456
3rm618ZCyclin-dependent kinase 22.7.11.220.455
4fki09KCyclin-dependent kinase 22.7.11.220.455
3s2pPMUCyclin-dependent kinase 22.7.11.220.454
1ckpPVBCyclin-dependent kinase 22.7.11.220.453
3qu0X40Cyclin-dependent kinase 22.7.11.220.452
4fkj11KCyclin-dependent kinase 22.7.11.220.447
2btsU32Cyclin-dependent kinase 22.7.11.220.446
5aniES4Cyclin-dependent kinase 22.7.11.220.445
1ke7LS3Cyclin-dependent kinase 22.7.11.220.443
3qtzX42Cyclin-dependent kinase 22.7.11.220.442
2c69CT8Cyclin-dependent kinase 22.7.11.220.440