sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 1.000 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.571 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.562 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.559 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.552 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.550 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.549 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.546 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.543 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.541 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.540 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.539 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.537 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.535 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.532 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.532 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.529 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.528 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.528 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.527 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.526 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.525 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.522 | |
| 1uyc | PU7 | Heat shock protein HSP 90-alpha | / | 0.521 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.519 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.518 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.517 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.516 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.511 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.510 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.508 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.508 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.503 | |
| 2wi4 | ZZ4 | Heat shock protein HSP 90-alpha | / | 0.502 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.501 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.499 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.495 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.488 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.468 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.467 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.464 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.464 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.451 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.450 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.449 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.448 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.448 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.445 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.443 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 4l4x | NDP | AmphI | / | 0.442 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.441 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.440 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.440 |