sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1y1r	ANU	Uridine phosphorylase	2.4.2.3

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1y1r	ANU	Uridine phosphorylase	2.4.2.3	1.000
1u1g	BBB	Uridine phosphorylase	2.4.2.3	0.574
3c74	ANU	Uridine phosphorylase	2.4.2.3	0.570
2hwu	URI	Uridine phosphorylase	2.4.2.3	0.517
5c80	URI	Uridine phosphorylase	/	0.506
1tgv	5UD	Uridine phosphorylase	2.4.2.3	0.490
4g8j	THM	Uridine phosphorylase	/	0.483
2isc	223	Purine nucleoside phosphorylase, putative	/	0.479
1u1d	181	Uridine phosphorylase	2.4.2.3	0.475
4ogk	THM	Uridine phosphorylase	2.4.2.3	0.460
1q1g	MTI	Purine nucleoside phosphorylase	/	0.459
1nw4	IMH	Purine nucleoside phosphorylase	/	0.446