sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1fxu	GU7	Purine nucleoside phosphorylase	2.4.2.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1fxu	GU7	Purine nucleoside phosphorylase	2.4.2.1	1.000
1a9s	NOS	Purine nucleoside phosphorylase	2.4.2.1	0.592
2a0x	DIH	Purine nucleoside phosphorylase	2.4.2.1	0.543
1yry	MSG	Purine nucleoside phosphorylase	2.4.2.1	0.523
1pwy	AC2	Purine nucleoside phosphorylase	2.4.2.1	0.488
1rfg	GMP	Purine nucleoside phosphorylase	2.4.2.1	0.478
2on6	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.472
1pf7	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.469
1a9p	9DI	Purine nucleoside phosphorylase	2.4.2.1	0.460
1b8o	IMH	Purine nucleoside phosphorylase	2.4.2.1	0.453
1b8n	IMG	Purine nucleoside phosphorylase	2.4.2.1	0.448
1v2h	GUN	Purine nucleoside phosphorylase	2.4.2.1	0.441