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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1finATPCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1finATPCyclin-dependent kinase 22.7.11.221.000
4bcmT7ZCyclin-dependent kinase 22.7.11.220.549
1fvv107Cyclin-dependent kinase 22.7.11.220.500
2vu3LZECyclin-dependent kinase 22.7.11.220.488
3tnwF18Cyclin-dependent kinase 22.7.11.220.484
2btsU32Cyclin-dependent kinase 22.7.11.220.479
3my5RFZCyclin-dependent kinase 22.7.11.220.479
3qxpX64Cyclin-dependent kinase 22.7.11.220.478
2uzbC75Cyclin-dependent kinase 22.7.11.220.470
3s1h56ZCyclin-dependent kinase 22.7.11.220.469
4l9i8PRRhodopsin kinase/0.469
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.469
2c4g514Cyclin-dependent kinase 22.7.11.220.468
3rak03ZCyclin-dependent kinase 22.7.11.220.465
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.464
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.462
2w05FRTCyclin-dependent kinase 22.7.11.220.457
3ezvEZVCyclin-dependent kinase 22.7.11.220.457
2uzdC85Cyclin-dependent kinase 22.7.11.220.456
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.455
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.454
1ke5LS1Cyclin-dependent kinase 22.7.11.220.451
4ii5ADPCyclin-dependent kinase 22.7.11.220.451
2wpa889Cyclin-dependent kinase 22.7.11.220.450
3js2VM1Fibroblast growth factor receptor 1/0.450
2fvdLIACyclin-dependent kinase 22.7.11.220.449
3c4xATPRhodopsin kinase/0.447
1pxmCK5Cyclin-dependent kinase 22.7.11.220.446
2ckeIQUDeath-associated protein kinase 2/0.446
4fx360KCyclin-dependent kinase 22.7.11.220.446
3r1yX76Cyclin-dependent kinase 22.7.11.220.445
1w0xOLOCyclin-dependent kinase 22.7.11.220.444
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.444
2vv9IM9Cyclin-dependent kinase 22.7.11.220.443
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.441
3at4CCKCasein kinase II subunit alpha2.7.11.10.441
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.440
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.440