sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1avd | BTN | Avidin |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1avd | BTN | Avidin | / | 1.000 | |
| 2avi | BTN | Avidin | / | 0.575 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.558 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.537 | |
| 2c4i | BTN | Avidin | / | 0.523 | |
| 2uyw | BTN | Avd protein | / | 0.511 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.502 | |
| 2uz2 | BTN | Avd protein | / | 0.495 | |
| 3vgw | NVZ | Avidin | / | 0.488 | |
| 3vhh | VHH | Avidin | / | 0.482 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.478 | |
| 4bx7 | B4F | Streptavidin | / | 0.477 | |
| 2izk | GLL | Streptavidin | / | 0.476 | |
| 3ry2 | BTN | Streptavidin | / | 0.476 | |
| 4pd6 | URI | Nucleoside permease | / | 0.476 | |
| 2izl | IMI | Streptavidin | / | 0.462 | |
| 5dp2 | NAP | CurF | / | 0.462 | |
| 4gda | BTN | Streptavidin | / | 0.461 | |
| 1sre | HAB | Streptavidin | / | 0.460 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.460 | |
| 2izg | BTN | Streptavidin | / | 0.457 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.457 | |
| 2rto | IMI | Streptavidin | / | 0.457 | |
| 2rtn | IMI | Streptavidin | / | 0.456 | |
| 4o7u | THF | Thymidylate synthase | / | 0.456 | |
| 2rtg | BTN | Streptavidin | / | 0.454 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.454 | |
| 2izh | BTN | Streptavidin | / | 0.453 | |
| 2rtd | BTN | Streptavidin | / | 0.452 | |
| 1srf | MTB | Streptavidin | / | 0.451 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.450 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.450 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.450 | |
| 1srg | MHB | Streptavidin | / | 0.449 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 1df8 | BTN | Streptavidin | / | 0.448 | |
| 1stp | BTN | Streptavidin | / | 0.448 | |
| 4aox | FAD | Steroid monooxygenase | / | 0.448 | |
| 4bqu | CLR | Japanin | / | 0.447 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.446 | |
| 1rxh | BNI | Streptavidin | / | 0.444 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 2izf | BTN | Streptavidin | / | 0.444 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.443 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2rtf | BTN | Streptavidin | / | 0.443 | |
| 1lcw | SHM | Streptavidin | / | 0.442 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.442 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.442 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.441 | |
| 1sri | DMB | Streptavidin | / | 0.441 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.441 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.441 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.441 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.441 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.440 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 3vhm | NPK | Avidin | / | 0.440 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.440 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.440 |