Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.11.000
5fs8FADApoptosis-inducing factor 1, mitochondrial1.1.10.551
5fs6FADApoptosis-inducing factor 1, mitochondrial1.1.10.550
4liiFADApoptosis-inducing factor 1, mitochondrial1.1.10.518
1gv4FADApoptosis-inducing factor 1, mitochondrial1.1.10.517
4h4vFADBiphenyl dioxygenase ferredoxin reductase subunit/0.494
4bv6FADApoptosis-inducing factor 1, mitochondrial1.1.10.492
4h4pFADBiphenyl dioxygenase ferredoxin reductase subunit/0.487
3gd3FADApoptosis-inducing factor 1, mitochondrial1.1.10.486
4h4sFADBiphenyl dioxygenase ferredoxin reductase subunit/0.480
3lxdFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.474
2gr3FADFerredoxin reductase/0.468
3ef6FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component1.18.1.30.461
4emjFADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component1.18.1.30.459
4h50FADBiphenyl dioxygenase ferredoxin reductase subunit/0.451