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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5cgv0N8Polymerase acidic protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5cgv0N8Polymerase acidic protein/1.000
4e5h0N8Polymerase acidic protein/0.501
4awkCI1Polymerase acidic protein/0.482
4awgCI3Polymerase acidic protein/0.469
4avgSL6Polymerase acidic protein/0.465
2bf4FADNADPH--cytochrome P450 reductase/0.462
4ug91EWNitric oxide synthase oxygenase1.14.13.1650.460
1i9c5ADGlutamate mutase epsilon subunit/0.457
1r35I58Nitric oxide synthase, inducible1.14.13.390.450
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.444
2oz57XYUncharacterized protein/0.441
3rqmX2ENitric oxide synthase, brain1.14.13.390.441
5d8u0N8Polymerase acidic protein/0.441
3nlqJRRNitric oxide synthase, brain1.14.13.390.440