sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5c4i | TPP | Oxalate oxidoreductase subunit alpha |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5c4i | TPP | Oxalate oxidoreductase subunit alpha | / | 1.000 | |
| 5c4i | TPP | Oxalate oxidoreductase subunit beta | / | 1.000 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.537 | |
| 2uza | HTL | Pyruvate synthase | / | 0.531 | |
| 2c3y | HTL | Pyruvate synthase | / | 0.526 | |
| 1kek | HTL | Pyruvate synthase | / | 0.521 | |
| 5exd | TPP | Oxalate oxidoreductase subunit alpha | / | 0.515 | |
| 5exd | TPP | Oxalate oxidoreductase subunit beta | / | 0.515 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.505 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.499 | |
| 2pda | TPP | Pyruvate synthase | / | 0.480 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 4qpz | TPP | Benzaldehyde lyase | / | 0.465 | |
| 2c3u | 2TP | Pyruvate synthase | / | 0.464 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4qjq | OTR | Lactoperoxidase | / | 0.457 | |
| 2ag0 | TPP | Benzaldehyde lyase | / | 0.456 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.456 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.453 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.449 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.448 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.445 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.445 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.445 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.445 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.445 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.443 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.442 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.440 | |
| 4rd2 | GNP | Translation initiation factor 2 subunit gamma | / | 0.440 |