sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4v37 | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4v37 | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 1.000 | |
| 4pz2 | NAD | Aldehyde dehydrogenase 2-6 | / | 0.573 | |
| 2bhp | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.544 | |
| 4fqf | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.538 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.532 | |
| 2onp | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.532 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.530 | |
| 1o04 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.522 | |
| 2onm | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.521 | |
| 4a0m | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 0.519 | |
| 2j40 | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.518 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.516 | |
| 1o02 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.515 | |
| 3iwk | NAD | Aminoaldehyde dehydrogenase | / | 0.512 | |
| 2j5n | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.509 | |
| 4pt0 | NAD | Aldehyde dehydrogenase | / | 0.507 | |
| 4wb9 | NAI | Retinal dehydrogenase 1 | 1.2.1.36 | 0.506 | |
| 2eii | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.504 | |
| 1o00 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.502 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.495 | |
| 4oe2 | NAD | 2-aminomuconate 6-semialdehyde dehydrogenase | / | 0.495 | |
| 1nzw | NAI | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.492 | |
| 4fr8 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.487 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.485 | |
| 2bja | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.484 | |
| 3n82 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.484 | |
| 3iwj | NAD | Aminoaldehyde dehydrogenase | / | 0.481 | |
| 4i1w | NAD | 2-aminomuconate 6-semialdehyde dehydrogenase | / | 0.480 | |
| 4x4l | NAI | Retinal dehydrogenase 1 | 1.2.1.36 | 0.478 | |
| 3haz | NAD | Bifunctional protein PutA | / | 0.477 | |
| 4pxl | NAD | Aldehyde dehydrogenase3 | / | 0.477 | |
| 1cw3 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.476 | |
| 3ju8 | NAD | N-succinylglutamate 5-semialdehyde dehydrogenase | 1.2.1.71 | 0.470 | |
| 1nzz | NAI | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.464 | |
| 4fr8 | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.449 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.447 | |
| 3n83 | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.444 | |
| 4f3x | NAD | Putative aldehyde dehydrogenase | / | 0.442 | |
| 4x2q | NAD | Retinal dehydrogenase 2 | 1.2.1.36 | 0.440 |