Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4pl9ADPEthylene receptor 1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4pl9ADPEthylene receptor 1/1.000
1i5cADPChemotaxis protein CheA2.7.13.30.475
3zoiM2WIsopenicillin N synthase1.21.3.10.475
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.474
1i59ANPChemotaxis protein CheA2.7.13.30.473
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.472
4rh10TTSpore photoproduct lyase/0.472
4o4eATPKinase/0.471
3dgeADPSensor histidine kinase/0.467
4fhf0TTSpore photoproduct lyase/0.467
5dp2NAPCurF/0.465
2z2w770Wee1-like protein kinase2.7.10.20.464
1u0wSTLChalcone synthase 22.3.1.740.462
1zg32HIIsoflavone 4'-O-methyltransferase/0.462
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.461
3p9tTCLRepressor/0.460
1u1f183Uridine phosphorylase2.4.2.30.458
2vbdV10Isopenicillin N synthase1.21.3.10.458
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.455
1qiqACCIsopenicillin N synthase1.21.3.10.453
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.453
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.453
1bifAGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.452
1iyzNDPProbable quinone oxidoreductase/0.450
2wo7ASVIsopenicillin N synthase1.21.3.10.450
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.449
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
2vbpVB1Isopenicillin N synthase1.21.3.10.449
2vcmM11Isopenicillin N synthase1.21.3.10.449
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.449
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
1obnASVIsopenicillin N synthase1.21.3.10.448
4b6uM7GEukaryotic translation initiation factor 4E type 3/0.447
1s3uTQDDihydrofolate reductase1.5.1.30.446
2in6839Wee1-like protein kinase2.7.10.20.446
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.446
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
2y6fM9FIsopenicillin N synthase1.21.3.10.445
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.445
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.445
4ko8AGSTransitional endoplasmic reticulum ATPase3.6.4.60.445
1i59ADPChemotaxis protein CheA2.7.13.30.444
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
2jb4A14Isopenicillin N synthase1.21.3.10.444
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.443
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.443
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1i5bANPChemotaxis protein CheA2.7.13.30.440
2yg5FADPutrescine oxidase/0.440
4iarERM5-hydroxytryptamine receptor 1B/0.440
3qakUKAAdenosine receptor A2a/0.440