sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nmj | NAP | Aldehyde dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4nmj | NAP | Aldehyde dehydrogenase | / | 1.000 | |
| 4nmk | NAP | Aldehyde dehydrogenase | / | 0.616 | |
| 4h73 | NDP | Aldehyde dehydrogenase | / | 0.577 | |
| 4oe2 | NAD | 2-aminomuconate 6-semialdehyde dehydrogenase | / | 0.528 | |
| 2j40 | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.498 | |
| 2ehq | NAP | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.497 | |
| 4i1w | NAD | 2-aminomuconate 6-semialdehyde dehydrogenase | / | 0.496 | |
| 4v37 | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 0.486 | |
| 2j5n | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.481 | |
| 2d4e | NAD | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenaseiheyensis HTE831] | / | 0.480 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.480 | |
| 2bhp | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.473 | |
| 2bja | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.469 | |
| 1uxn | NAP | NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.467 | |
| 2eii | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.467 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.464 | |
| 3iwk | NAD | Aminoaldehyde dehydrogenase | / | 0.462 | |
| 4fqf | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.461 | |
| 4pz2 | NAD | Aldehyde dehydrogenase 2-6 | / | 0.457 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.457 | |
| 4f3x | NAD | Putative aldehyde dehydrogenase | / | 0.454 | |
| 4a0m | NAD | Betaine aldehyde dehydrogenase, chloroplastic | 1.2.1.8 | 0.448 | |
| 2wme | NAP | NAD/NADP-dependent betaine aldehyde dehydrogenase | / | 0.446 | |
| 4wb9 | NAI | Retinal dehydrogenase 1 | 1.2.1.36 | 0.446 | |
| 2esd | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.9 | 0.445 | |
| 1o02 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.444 | |
| 2onp | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.442 | |
| 3rhh | NAP | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 3v9l | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.440 |