sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4lb2 | DM5 | Serum albumin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4lb2 | DM5 | Serum albumin | / | 1.000 | |
| 4la0 | 198 | Serum albumin | / | 0.572 | |
| 3lu8 | IQX | Serum albumin | / | 0.512 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.467 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.461 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 4l9k | EHF | Serum albumin | / | 0.460 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.454 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.452 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.451 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.450 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 4l8u | 9AZ | Serum albumin | / | 0.449 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.448 | |
| 4l9q | 9TP | Serum albumin | / | 0.448 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.447 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.447 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.446 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.445 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.443 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.442 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 |