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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4f5yC2EStimulator of interferon genes protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4f5yC2EStimulator of interferon genes protein/1.000
4loi1YCStimulator of interferon genes protein/0.562
4emtC2EStimulator of interferon genes protein/0.537
5cfpC2EStimulator of interferon genes protein/0.522
5cflC2EStimulator of interferon genes protein/0.490
4f9gC2EStimulator of interferon genes protein/0.488
4ef4C2EStimulator of interferon genes protein/0.487
4loh1SYStimulator of interferon genes protein/0.481
4f5dC2EStimulator of interferon genes protein/0.476
3muoZPRProlyl endopeptidase/0.472
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.452
5cfn2BAStimulator of interferon genes protein/0.452
4yp12BAStimulator of interferon genes protein/0.451
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1u3dFADCryptochrome-1/0.442
4qxr1YEStimulator of interferon genes protein/0.442
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.440
3nsh957Beta-secretase 13.4.23.460.440
4i0i957Beta-secretase 13.4.23.460.440