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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4emrMGPRibosome inactivating protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4emrMGPRibosome inactivating protein/1.000
3qjiMGPRibosome inactivating protein/0.663
4lwxMU2Ribosome inactivating protein/0.612
4jtpASCRibosome inactivating protein/0.594
3u8fFGMRibosome inactivating protein/0.571
5ilwURIRibosome inactivating protein/0.554
1mrkFMCRibosome-inactivating protein alpha-trichosanthin3.2.2.220.521
4zz6CTPRibosome inactivating protein/0.484
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.462
1mvtDTMDihydrofolate reductase1.5.1.30.454
1obnASVIsopenicillin N synthase1.21.3.10.451
1drfFOLDihydrofolate reductase1.5.1.30.449
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.448
1z5uCMPClass B acid phosphatase/0.446
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.445
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.441
1lpcCMPAntiviral protein DAP-303.2.2.220.440
2g1a5HGClass B acid phosphatase3.1.3.20.440
2vbpVB1Isopenicillin N synthase1.21.3.10.440