sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 1.000 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.917 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.881 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.827 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.678 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.672 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.657 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.655 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.651 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.646 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.644 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.642 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.641 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.639 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.636 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.633 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.631 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.628 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.627 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.621 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.620 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.609 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.609 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.595 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.591 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.589 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.587 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.584 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.583 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.582 | |
| 4jx1 | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.555 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.551 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.523 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.521 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.497 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.492 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.490 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.489 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.487 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.485 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.484 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.480 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.479 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.476 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.475 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.471 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.471 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.468 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.467 | |
| 2y3s | TIR | TamL | / | 0.465 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.462 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.461 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.459 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.458 | |
| 3eej | 53R | Uncharacterized protein | / | 0.455 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.449 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.449 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.449 | |
| 1m9r | INE | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.447 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.447 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.445 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.444 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.444 | |
| 1vzd | CB3 | Thymidylate synthase | / | 0.443 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.441 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.441 |