sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4c2p | X8Z | Angiotensin-converting enzyme | 3.2.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4c2p | X8Z | Angiotensin-converting enzyme | 3.2.1 | 1.000 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.618 | |
| 2oc2 | RX3 | Angiotensin-converting enzyme | 3.2.1 | 0.600 | |
| 1uze | EAL | Angiotensin-converting enzyme | 3.2.1 | 0.581 | |
| 2x94 | X94 | Angiotensin-converting enzyme | 3.4.15.1 | 0.570 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.540 | |
| 1o86 | LPR | Angiotensin-converting enzyme | 3.2.1 | 0.526 | |
| 1j36 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.516 | |
| 2x95 | X95 | Angiotensin-converting enzyme | 3.4.15.1 | 0.503 | |
| 4ca7 | 3EF | Angiotensin-converting enzyme | 3.4.15.1 | 0.500 | |
| 4ca8 | 3ES | Angiotensin-converting enzyme | 3.4.15.1 | 0.490 | |
| 2x92 | X92 | Angiotensin-converting enzyme | 3.4.15.1 | 0.478 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.477 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.473 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.467 | |
| 4bxk | 1IU | Angiotensin-converting enzyme | 3.2.1 | 0.462 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.453 | |
| 4ca5 | 3EF | Angiotensin-converting enzyme | 3.2.1 | 0.452 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.451 | |
| 4itm | ATP | Tetraacyldisaccharide 4'-kinase | / | 0.446 | |
| 3br2 | DEQ | HTH-type transcriptional regulator QacR | / | 0.444 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.441 |