sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4blr | UTP | NTPase P4 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4blr | UTP | NTPase P4 | / | 1.000 | |
| 4bls | APC | NTPase P4 | / | 0.532 | |
| 2vht | ATP | NTPase P4 | / | 0.504 | |
| 1w48 | APC | NTPase P4 | / | 0.496 | |
| 1w49 | APC | NTPase P4 | / | 0.494 | |
| 4blt | APC | NTPase P4 | / | 0.480 | |
| 1w4a | APC | NTPase P4 | / | 0.475 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.452 | |
| 2vhq | ATP | NTPase P4 | / | 0.442 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.442 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.440 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.440 |