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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3sqpFADGlutathione reductase, mitochondrial1.8.1.7

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3sqpFADGlutathione reductase, mitochondrial1.8.1.71.000
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.619
1k4qFADGlutathione reductase, mitochondrial1.8.1.70.618
1grhFADGlutathione reductase, mitochondrial1.8.1.70.617
1grgFADGlutathione reductase, mitochondrial1.8.1.70.605
3grsFADGlutathione reductase, mitochondrial1.8.1.70.601
1greFADGlutathione reductase, mitochondrial1.8.1.70.600
1bwcFADGlutathione reductase, mitochondrial1.8.1.70.599
4gr1FADGlutathione reductase, mitochondrial1.8.1.70.595
1gsnFADGlutathione reductase, mitochondrial1.8.1.70.589
1graFADGlutathione reductase, mitochondrial1.8.1.70.573
3dk8FADGlutathione reductase, mitochondrial1.8.1.70.571
3dk9FADGlutathione reductase, mitochondrial1.8.1.70.561
3dk4FADGlutathione reductase, mitochondrial1.8.1.70.550
2r9zFADGlutathione amide reductase/0.539
3djgFADGlutathione reductase, mitochondrial1.8.1.70.539
4kprFADThioredoxin reductase 1, cytoplasmic1.8.1.90.516
1grbFADGlutathione reductase, mitochondrial1.8.1.70.512
3dgzFADThioredoxin reductase 2, mitochondrial1.8.1.90.511
2v6oFADThioredoxin glutathione reductase/0.505
3qfbFADThioredoxin reductase 1, cytoplasmic1.8.1.90.504
2cfyFADThioredoxin reductase 1, cytoplasmic1.8.1.90.499
1febFADTrypanothione reductase1.8.1.120.490
2j3nFADThioredoxin reductase 1, cytoplasmic1.8.1.90.485
1gerFADGlutathione reductase1.8.1.70.484
2rabFADGlutathione amide reductase/0.479
1h6vFADThioredoxin reductase 1, cytoplasmic1.8.1.90.459
1bzlFADTrypanothione reductase1.8.1.120.451
4j56FADThioredoxin reductase 21.8.1.90.451
1zk7FADMercuric reductase1.16.1.10.449
1zx9FADMercuric reductase1.16.1.10.449
2nvkFADThioredoxin reductase 1, mitochondrial1.8.1.90.448
1onfFADGlutathione reductase1.8.1.70.443