Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3r94FLRAldo-keto reductase family 1 member C3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3r94FLRAldo-keto reductase family 1 member C3/1.000
3r7mSUZAldo-keto reductase family 1 member C3/0.712
3ufyNPXAldo-keto reductase family 1 member C3/0.708
3r6iJMSAldo-keto reductase family 1 member C3/0.676
3uweVJJAldo-keto reductase family 1 member C3/0.672
3r43ID8Aldo-keto reductase family 1 member C3/0.671
4hmn16JAldo-keto reductase family 1 member C3/0.667
3r8gIZPAldo-keto reductase family 1 member C3/0.657
4h7c10HAldo-keto reductase family 1 member C3/0.655
1zq5E04Aldo-keto reductase family 1 member C3/0.642
3r8hZOMAldo-keto reductase family 1 member C3/0.637
1s2cFLFAldo-keto reductase family 1 member C3/0.631
1ry0PG2Aldo-keto reductase family 1 member C3/0.616
4dbw511Aldo-keto reductase family 1 member C3/0.604
3r58NPSAldo-keto reductase family 1 member C3/0.603
4fam0SZAldo-keto reductase family 1 member C3/0.603
2f3815MAldo-keto reductase family 1 member C3/0.587
4dbs0HVAldo-keto reductase family 1 member C3/0.578
4fa30SLAldo-keto reductase family 1 member C3/0.574
3ug8IMNAldo-keto reductase family 1 member C3/0.570
4fal0T0Aldo-keto reductase family 1 member C3/0.562
4dbuBT9Aldo-keto reductase family 1 member C3/0.557
3ugrIMNAldo-keto reductase family 1 member C3/0.553
1ry8RUTAldo-keto reductase family 1 member C3/0.528
2vz0D64Pteridine reductase/0.483
1s36CEIObelin/0.478
3v94WYQPhosphodiesterase/0.478
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.456
1uhjCZBAequorin-2/0.452
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.452
3jq7DX2Pteridine reductase, putative/0.452
3irxUDRGag-Pol polyprotein2.7.7.490.450
1xf0ASDAldo-keto reductase family 1 member C3/0.449
4bfuZVUPantothenate kinase2.7.1.330.448
1zgcA2EAcetylcholinesterase3.1.1.70.447
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.446
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
3bmcFOLPteridine reductase/0.444
3g72A6TRenin3.4.23.150.444
3rsv3RSBeta-secretase 13.4.23.460.444
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1lnmDTXBilin-binding protein/0.443
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.443
4b2gV1NUncharacterized protein/0.443
2bktRPFRenin3.4.23.150.442
2d06ESTSulfotransferase 1A12.8.2.10.442
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.442
4mt92D6Tankyrase-12.4.2.300.442
1pq6965Oxysterols receptor LXR-beta/0.441
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.441
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.441
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.441
2xuhTZ4Acetylcholinesterase3.1.1.70.440
3b9oFMNAlkane monoxygenase/0.440
3jq8DX3Pteridine reductase, putative/0.440
4jq2SUZAldo-keto reductase family 1 member C2/0.440