sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3nr4 | PYV | Abscisic acid receptor PYL2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 1.000 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.739 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.592 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.524 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.478 | |
| 3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.476 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.473 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.471 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.469 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.467 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.465 | |
| 3nmn | PYV | Abscisic acid receptor PYL1 | / | 0.460 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.453 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.451 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1fml | RTL | Retinol dehydratase | / | 0.448 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.448 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.448 | |
| 3oji | PYV | Abscisic acid receptor PYL3 | / | 0.448 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.447 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 3zvu | A8S | Abscisic acid receptor PYR1 | / | 0.445 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.445 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.444 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.442 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.440 |