Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
3l70 | JZV | Cytochrome b |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
3l70 | JZV | Cytochrome b | / | 1.000 | |
3tgu | WF3 | Cytochrome b | / | 0.625 | |
3l71 | AZO | Cytochrome b | / | 0.609 | |
1sqb | AZO | Cytochrome b | / | 0.561 | |
1sqp | MYX | Cytochrome b | / | 0.555 | |
3h1j | SMA | Cytochrome b | / | 0.496 | |
4j6c | STR | Cytochrome P450 monooxygenase | / | 0.484 | |
4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.483 | |
4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.483 | |
3aba | FLI | Cytochrome P450 | / | 0.479 | |
2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.474 | |
3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.473 | |
2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.470 | |
3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.470 | |
1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.467 | |
1iyz | NDP | Probable quinone oxidoreductase | / | 0.463 | |
4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.463 | |
4jqh | 1MF | Alr2278 protein | / | 0.462 | |
2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.461 | |
2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.460 | |
1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.459 | |
4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.458 | |
4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.458 | |
4qe6 | JN3 | Bile acid receptor | / | 0.458 | |
1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.457 | |
3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.457 | |
1fml | RTL | Retinol dehydratase | / | 0.456 | |
1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
1sqq | OST | Cytochrome b | / | 0.455 | |
2ibz | SMA | Cytochrome b | / | 0.455 | |
3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.455 | |
4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.455 | |
2aib | ERG | Beta-elicitin cinnamomin | / | 0.454 | |
2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
3p3z | P3Z | Putative cytochrome P450 | / | 0.454 | |
3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.454 | |
4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.454 | |
2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.453 | |
2h42 | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
3bhl | THG | Thymidylate synthase | / | 0.452 | |
3vtd | TKD | Vitamin D3 receptor | / | 0.451 | |
4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.451 | |
1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.450 | |
1tw2 | ERT | Carminomycin 4-O-methyltransferase DnrK | 2.1.1.292 | 0.450 | |
1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.449 | |
2w4q | CBW | Prostaglandin reductase 2 | 1.3.1.48 | 0.448 | |
4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.448 | |
3l6j | Z90 | Alr2278 protein | / | 0.447 | |
5k2b | ZMA | Adenosine receptor A2a | / | 0.447 | |
1lri | CLR | Beta-elicitin cryptogein | / | 0.446 | |
1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
3a1l | 2CC | Cytochrome P450 | / | 0.446 | |
3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.446 | |
3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
1kzj | CB3 | Thymidylate synthase | / | 0.444 | |
2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
3p9t | TCL | Repressor | / | 0.444 | |
4l9q | 9TP | Serum albumin | / | 0.444 | |
5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.444 | |
5jtb | ZMA | Adenosine receptor A2a | / | 0.444 | |
1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.443 | |
1pp9 | SMA | Cytochrome b | / | 0.443 | |
2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.443 | |
3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
3jyn | NDP | Quinone oxidoreductase | / | 0.442 | |
4isk | 1JY | Thymidylate synthase | / | 0.442 | |
1osv | CHC | Bile acid receptor | / | 0.441 | |
2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.441 | |
3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
3tda | PN0 | Cytochrome P450 2D6 | / | 0.441 | |
4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.441 | |
1tdu | CB3 | Thymidylate synthase | / | 0.440 | |
2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.440 | |
3nal | DBK | Calcium-transporting ATPase | / | 0.440 | |
4gev | CB3 | Thymidylate synthase | / | 0.440 |