sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 1.000 | |
| 5av3 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.487 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.486 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.484 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.474 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.473 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.470 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.469 | |
| 3gu7 | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.467 | |
| 2yaa | ATP | Death-associated protein kinase 2 | / | 0.461 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.461 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.458 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.458 | |
| 1zp9 | ATP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.455 | |
| 3p23 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.455 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.454 | |
| 4eoo | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 3beg | ANP | SRSF protein kinase 1 | 2.7.11.1 | 0.449 | |
| 4l9i | 8PR | Rhodopsin kinase | / | 0.449 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.448 | |
| 3nux | 3NV | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.447 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 5aut | 2AN | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3i60 | E86 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.444 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.443 | |
| 4fv3 | EK6 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.441 |