sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 1.000 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.697 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.672 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.666 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.643 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.642 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.627 | |
| 3iob | A4D | Pantothenate synthetase | 6.3.2.1 | 0.627 | |
| 3coz | 54H | Pantothenate synthetase | 6.3.2.1 | 0.592 | |
| 4de5 | 0JD | Pantothenate synthetase | 6.3.2.1 | 0.554 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.543 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.536 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.526 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.524 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.501 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.498 | |
| 3ivx | FG6 | Pantothenate synthetase | 6.3.2.1 | 0.496 | |
| 1n2j | PAF | Pantothenate synthetase | 6.3.2.1 | 0.491 | |
| 2x3f | APC | Pantothenate synthetase | / | 0.480 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.478 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.474 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.471 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.461 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.458 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.457 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.452 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1owl | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3n1s | 5GP | Purine nucleoside phosphoramidase | / | 0.445 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.442 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.440 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.440 |