sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 1.000 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.628 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.546 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.500 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.490 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.481 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.475 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.472 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.469 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.469 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.469 | |
| 4k9v | 6AW | Cytochrome P450 3A4 | / | 0.464 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.463 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.463 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 2w0b | CMW | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.455 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.455 | |
| 4jx1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.455 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.451 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.448 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.444 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.442 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.442 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 |