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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3e33ED7Protein farnesyltransferase subunit beta2.5.1.58

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3e33ED7Protein farnesyltransferase subunit beta2.5.1.581.000
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.667
1s63778Protein farnesyltransferase subunit beta2.5.1.580.665
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.644
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.640
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.636
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.635
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.634
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.632
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.620
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.614
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.604
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.590
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.581
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.563
3q7fED2Uncharacterized protein/0.547
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.523
3sfy3FYUncharacterized protein/0.521
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.506
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.506
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.500
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.496
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.493
4gto7TOProtein farnesyltransferase subunit beta2.5.1.580.493
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.480
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.463
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.455
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.445
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.440
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.440
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.440