sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3cx8 | GSP | Guanine nucleotide-binding protein subunit alpha-13 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3cx8 | GSP | Guanine nucleotide-binding protein subunit alpha-13 | / | 1.000 | |
| 3cx6 | GDP | Guanine nucleotide-binding protein subunit alpha-13 | / | 0.575 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.478 | |
| 1zcb | GDP | Guanine nucleotide-binding protein subunit alpha-13 | / | 0.466 | |
| 4e07 | ACP | Plasmid partitioning protein ParF | / | 0.459 | |
| 3t1t | GDP | Probable gliding protein mglA | / | 0.458 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.455 | |
| 2xtz | GSP | Guanine nucleotide-binding protein alpha-1 subunit | / | 0.453 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.450 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.449 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.448 | |
| 4xj3 | GTP | Cyclic GMP-AMP synthase | / | 0.448 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.444 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.444 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.442 | |
| 1bof | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.441 | |
| 1t44 | ATP | Actin, alpha skeletal muscle | / | 0.441 | |
| 1yp3 | ATP | Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic | 2.7.7.27 | 0.441 | |
| 3h65 | I2C | 5,10-methenyltetrahydromethanopterin hydrogenase | 1.12.98.2 | 0.441 |