sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2x7e | X7E | Kinesin-like protein KIF11 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2x7e | X7E | Kinesin-like protein KIF11 | / | 1.000 | |
| 3k5e | K5E | Kinesin-like protein KIF11 | / | 0.617 | |
| 2x7d | EGB | Kinesin-like protein KIF11 | / | 0.615 | |
| 2ieh | MOY | Kinesin-like protein KIF11 | / | 0.612 | |
| 2g1q | N9H | Kinesin-like protein KIF11 | / | 0.606 | |
| 1x88 | NAT | Kinesin-like protein KIF11 | / | 0.602 | |
| 2x2r | X2O | Kinesin-like protein KIF11 | / | 0.596 | |
| 2xae | 2XA | Kinesin-like protein KIF11 | / | 0.591 | |
| 4bbg | V02 | Kinesin-like protein KIF11 | / | 0.589 | |
| 1q0b | NAT | Kinesin-like protein KIF11 | / | 0.579 | |
| 2q2z | MKK | Kinesin-like protein KIF11 | / | 0.578 | |
| 2wog | ZZD | Kinesin-like protein KIF11 | / | 0.577 | |
| 2x7c | KZ9 | Kinesin-like protein KIF11 | / | 0.567 | |
| 3k3b | L31 | Kinesin-like protein KIF11 | / | 0.560 | |
| 2fme | 3QC | Kinesin-like protein KIF11 | / | 0.545 | |
| 3ken | ZZD | Kinesin-like protein KIF11 | / | 0.541 | |
| 2gm1 | 2AZ | Kinesin-like protein KIF11 | / | 0.524 | |
| 4a51 | DQ8 | Kinesin-like protein KIF11 | / | 0.512 | |
| 4a5y | G7X | Kinesin-like protein KIF11 | / | 0.493 | |
| 4as7 | 6LX | Kinesin-like protein KIF11 | / | 0.465 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.464 | |
| 3qql | X03 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4ysw | NAI | Xanthine dehydrogenase/oxidase | / | 0.459 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2itx | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.456 | |
| 2wi1 | ZZ2 | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 1ckp | PVB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3qx4 | X4B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 1fvt | 106 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3b9l | AZZ | Serum albumin | / | 0.452 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4fkj | 11K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.448 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3qwj | X6A | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.447 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 4eom | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.444 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.443 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 4cdm | FAD | Deoxyribodipyrimidine photolyase | / | 0.443 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2bkz | SBC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4hyp | 1A1 | DNA gyrase subunit B | / | 0.442 | |
| 2bxe | 1FL | Serum albumin | / | 0.441 | |
| 2q7h | YLY | Pyrrolysine--tRNA ligase | / | 0.441 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4jq7 | KJQ | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 4yqf | GDP | Septin-9 | / | 0.441 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2uxu | NAR | HTH-type transcriptional regulator TtgR | / | 0.440 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.440 |