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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2vcwZZAHematopoietic prostaglandin D synthase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2vcwZZAHematopoietic prostaglandin D synthase/1.000
2vd0D27Hematopoietic prostaglandin D synthase/0.587
2vcxD26Hematopoietic prostaglandin D synthase/0.574
3kxoKXOHematopoietic prostaglandin D synthase/0.567
4edz0O5Hematopoietic prostaglandin D synthase/0.562
2vczVC3Hematopoietic prostaglandin D synthase/0.556
3vi7CBDHematopoietic prostaglandin D synthase/0.541
2vcqD25Hematopoietic prostaglandin D synthase/0.511
4edy9PQHematopoietic prostaglandin D synthase/0.492
3vi5M4MHematopoietic prostaglandin D synthase/0.484
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.465
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.452
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.451
3pqbVGPPutative oxidoreductase/0.450
1blzACVIsopenicillin N synthase1.21.3.10.449
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
2wo7ASVIsopenicillin N synthase1.21.3.10.444
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.440