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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.695
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.622
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.597
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.574
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.566
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.559
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.558
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.556
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.552
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.551
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.548
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.548
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.545
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.540
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.536
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.530
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.526
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.520
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.513
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.511
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.509
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.498
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
2uvyGVIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
3mvhWFERAC-alpha serine/threonine-protein kinase2.7.11.10.478
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
4yxsEMUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
3nynSGVG protein-coupled receptor kinase 62.7.11.160.446
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3dneLL1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440