Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
2uvz | GVJ | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
2uvz | GVJ | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 1.000 | |
2uw6 | GVO | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.640 | |
2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.607 | |
2vo6 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.601 | |
2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.597 | |
2f7z | 6EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.594 | |
2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.593 | |
2c1a | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.586 | |
2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.576 | |
3vqh | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.574 | |
2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.573 | |
2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.569 | |
1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.563 | |
2uzv | SS5 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.561 | |
2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.559 | |
1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.556 | |
3zo4 | QWI | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.555 | |
3ow3 | SMY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.553 | |
2uw4 | L15 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.551 | |
2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.548 | |
2vo0 | M03 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.543 | |
2uw0 | GVK | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.538 | |
2gnf | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.537 | |
2vo3 | M04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.534 | |
2uw5 | GVN | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.531 | |
1q8t | Y27 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.530 | |
1ydr | IQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.528 | |
3zo1 | SIJ | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.528 | |
2uw7 | GVP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.527 | |
4gv1 | 0XZ | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.523 | |
2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.522 | |
4c34 | STU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.521 | |
2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.518 | |
1veb | I05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.517 | |
2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.501 | |
3e8e | G98 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.501 | |
3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.494 | |
1svg | I04 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.493 | |
1q8u | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.489 | |
3bwj | ARX | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.486 | |
3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.481 | |
2vnw | M01 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.478 | |
1xh9 | R69 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.475 | |
2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.473 | |
4yxs | EMU | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.471 | |
2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.467 | |
2gnl | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
4l43 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.461 | |
4wbb | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.455 | |
3lin | E13 | Protease | / | 0.454 | |
4f9b | 0SY | Cell division cycle 7-related protein kinase | 2.7.11.1 | 0.454 | |
4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.453 | |
3kkv | B99 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
3dne | LL1 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
4y93 | 746 | Tyrosine-protein kinase | / | 0.450 | |
4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.448 | |
4y95 | 746 | Tyrosine-protein kinase | / | 0.448 | |
2jdv | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
3gi6 | D78 | Gag-Pol polyprotein | / | 0.446 | |
3mvh | WFE | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.445 | |
1rfq | LAR | Actin, alpha skeletal muscle | / | 0.444 | |
2idw | 017 | Protease | / | 0.443 | |
1q24 | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
3lzu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
2g20 | L1A | Renin | 3.4.23.15 | 0.441 | |
1vik | BAY | Gag-Pol polyprotein | / | 0.440 | |
2p3b | 3TL | V-1 PROTEASE protein | / | 0.440 | |
2p3b | 3TL | V-1 protease | / | 0.440 | |
3ekp | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 |