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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.640
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.607
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.601
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.597
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.594
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.593
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.586
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.576
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.574
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.573
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.569
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.561
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.559
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.556
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.555
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.553
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.551
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.548
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.538
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.537
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.534
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.531
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.530
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.528
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.528
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.527
4gv10XZRAC-alpha serine/threonine-protein kinase2.7.11.10.523
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.522
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.521
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.518
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.475
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
4yxsEMUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.471
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
3l9nL9NcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.466
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.461
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
1tj1FADBifunctional protein PutA1.5.5.20.455
3linE13Protease/0.454
4f9b0SYCell division cycle 7-related protein kinase2.7.11.10.454
4hge15VTyrosine-protein kinase JAK2/0.453
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3dneLL1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4y93746Tyrosine-protein kinase/0.450
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.448
4y95746Tyrosine-protein kinase/0.448
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
3gi6D78Gag-Pol polyprotein/0.446
3mvhWFERAC-alpha serine/threonine-protein kinase2.7.11.10.445
1rfqLARActin, alpha skeletal muscle/0.444
2idw017Protease/0.443
1q24ATPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
3lzu017Gag-Pol polyprotein3.4.23.160.442
4qgiROCGag-Pol polyprotein3.4.23.160.442
2g20L1ARenin3.4.23.150.441
1vikBAYGag-Pol polyprotein/0.440
2p3b3TLV-1 PROTEASE protein/0.440
2p3b3TLV-1 protease/0.440
3ekp478Gag-Pol polyprotein3.4.23.160.440