sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2klh | 5GP | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2klh | 5GP | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 1.000 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.464 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.457 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.457 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.453 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.452 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.451 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.450 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.449 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.447 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.447 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.446 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.446 | |
| 1tys | TMP | Thymidylate synthase | / | 0.445 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.445 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.444 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.444 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.443 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.442 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.442 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.441 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.441 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.440 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.440 |