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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2gnfY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.606
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.597
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.570
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.568
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.556
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.549
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.538
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.533
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.532
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.527
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.526
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.523
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.520
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.519
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.516
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.515
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.514
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.505
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.503
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.501
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
4f9b0SYCell division cycle 7-related protein kinase2.7.11.10.489
2uvzGVJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
3l9mL9McAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.482
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.481
4j95ACPFibroblast growth factor receptor 2/0.481
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2etrY27Rho-associated protein kinase 12.7.11.10.476
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.470
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
4otiMI1Serine/threonine-protein kinase N1/0.469
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.468
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
4wbbADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.465
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
4hvi19STyrosine-protein kinase JAK32.7.10.20.462
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.458
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.455
2gnlH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
4anmWULCasein kinase II subunit alpha2.7.11.10.454
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.454
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
2f2uM77Rho-associated protein kinase 22.7.11.10.452
4o0wADNAurora kinase A2.7.11.10.452
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.451
1bx6BA1cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2ckeIQUDeath-associated protein kinase 2/0.449
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.445
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4jia1K3Tyrosine-protein kinase JAK2/0.444
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440