scPDB - Distribution of Binding site Similarity values of 2f8l entry / Site 1

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2f8l	SAM	Lmo1582 protein

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
2f8l	SAM	Lmo1582 protein	/	1.000
3ha5	SFG	Hydroxymycolate synthase MmaA4	2.1.1	0.502
1ve3	SAM	Uncharacterized protein	/	0.499
3s1s	SAH	Restriction endonuclease BpuSI	/	0.498
1nbi	SAM	Glycine N-methyltransferase	2.1.1.20	0.493
1skm	SAH	Modification methylase HhaI	2.1.1.37	0.487
4obw	SAM	2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial	/	0.480
3dhe	AND	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.475
2z6u	SAH	Modification methylase HhaI	2.1.1.37	0.471
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.471
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.470
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.468
3qlr	NDP	Dihydrofolate reductase	1.5.1.3	0.466
1so2	666	cGMP-inhibited 3',5'-cyclic phosphodiesterase B	3.1.4.17	0.465
3ha7	B32	Hydroxymycolate synthase MmaA4	2.1.1	0.464
3p8z	SAH	Genome polyprotein	2.1.1.56	0.463
5f2k	SAH	Uncharacterized protein	/	0.461
10mh	SAH	Modification methylase HhaI	2.1.1.37	0.460
3qv2	SAH	5-cytosine DNA methyltransferase	/	0.460
3kpk	FAD	Sulfide-quinone reductase	/	0.459
4gev	CB3	Thymidylate synthase	/	0.457
4tuv	CPZ	Cytochrome P450 119	1.14	0.457
1a4i	NDP	C-1-tetrahydrofolate synthase, cytoplasmic	1.5.1.5	0.456
1rx1	NAP	Dihydrofolate reductase	1.5.1.3	0.456
4ri1	ACO	UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	2.3.1.202	0.456
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.455
2h2q	NAP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.455
4c7k	NAP	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.454
5iu4	ZMA	Adenosine receptor A2a	/	0.454
2rbe	NDP	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.453
3jzi	JZL	Biotin carboxylase	6.3.4.14	0.452
1iol	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.451
1xdd	AAY	Integrin alpha-L	/	0.451
2uyh	SAH	Modification methylase HhaI	2.1.1.37	0.451
4mht	SAH	Modification methylase HhaI	2.1.1.37	0.451
5hwq	CAA	Hydroxymethylglutaryl-CoA synthase	/	0.451
1ia1	NDP	Dihydrofolate reductase	1.5.1.3	0.450
2aaz	CB3	Thymidylate synthase	2.1.1.45	0.450
3qvp	FAD	Glucose oxidase	1.1.3.4	0.450
3tm5	SFG	Uncharacterized protein	/	0.450
1kia	SAM	Glycine N-methyltransferase	2.1.1.20	0.449
2cmj	NAP	Isocitrate dehydrogenase [NADP] cytoplasmic	1.1.1.42	0.449
2pxa	SAH	Genome polyprotein	2.7.7.48	0.449
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.449
3rai	X85	Cyclin-dependent kinase 2	2.7.11.22	0.449
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.449
2iya	ZIO	Oleandomycin glycosyltransferase	/	0.448
3pt6	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.448
4q71	FAD	Bifunctional protein PutA	/	0.448
1fdt	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.447
1mjb	ACO	Histone acetyltransferase ESA1	/	0.447
4l4x	NDP	AmphI	/	0.447
4nu5	NAD	Phosphonate dehydrogenase	1.20.1.1	0.447
4qtu	SAM	18S rRNA (guanine(1575)-N(7))-methyltransferase	/	0.447
1r2j	FAD	FkbI	/	0.446
4wa9	AXI	Tyrosine-protein kinase ABL1	2.7.10.2	0.446
5dqr	FAD	7-hydroxymethyl chlorophyll a reductase, chloroplastic	1.17.7.2	0.446
5mht	SAH	Modification methylase HhaI	2.1.1.37	0.446
1qan	SAH	rRNA adenine N-6-methyltransferase	2.1.1.184	0.445
2fiw	ACO	GCN5-related N-acetyltransferase:Aminotransferase, class-II	/	0.445
2xvf	FAD	Putative flavin-containing monooxygenase	/	0.445
3oib	FDA	Putative acyl-CoA dehydrogenase	/	0.445
2p5u	NAD	UDP-glucose 4-epimerase	/	0.444
4j03	FVS	Bifunctional epoxide hydrolase 2	3.1.3.76	0.444
1jsc	TPP	Acetolactate synthase catalytic subunit, mitochondrial	2.2.1.6	0.443
3d5q	T30	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.443
3fpz	AHZ	Thiamine thiazole synthase	/	0.443
5e72	SAM	N2, N2-dimethylguanosine tRNA methyltransferase	/	0.443
5hsa	FAS	Alcohol oxidase 1	1.1.3.13	0.443
1ai9	NDP	Dihydrofolate reductase	1.5.1.3	0.442
1g4t	FTP	Thiamine-phosphate synthase	/	0.442
2jn3	JN3	Fatty acid-binding protein, liver	/	0.442
3lsh	FAD	Pyranose 2-oxidase	/	0.442
3mht	SAH	Modification methylase HhaI	2.1.1.37	0.442
5uvi	ZMA	Adenosine receptor A2a	/	0.442
1ghe	ACO	Acetyltransferase	2.3.1	0.441
2fto	CB3	Thymidylate synthase	/	0.441
2w06	FRV	Cyclin-dependent kinase 2	2.7.11.22	0.441
3ha3	SAH	Hydroxymycolate synthase MmaA4	2.1.1	0.441
3mte	SAM	16S rRNA (adenine(1408)-N(1))-methyltransferase	2.1.1.180	0.441
1fjx	SAH	Modification methylase HhaI	2.1.1.37	0.440
1kph	SAH	Cyclopropane mycolic acid synthase 1	2.1.1.79	0.440
1qao	SAM	rRNA adenine N-6-methyltransferase	2.1.1.184	0.440
2f4b	EHA	Peroxisome proliferator-activated receptor gamma	/	0.440
3ds6	A17	Mitogen-activated protein kinase 14	/	0.440
3pt9	SAH	DNA (cytosine-5)-methyltransferase 1	2.1.1.37	0.440
4hx5	19V	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.440