Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2c9cATPPsp operon transcriptional activator

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2c9cATPPsp operon transcriptional activator/1.000
4qosADPPsp operon transcriptional activator/0.537
2c96ATPPsp operon transcriptional activator/0.514
3m0eATPTranscriptional regulator (NtrC family)/0.485
3dzdADPTranscriptional regulator (NtrC family)/0.474
4orkGDPBifunctional AAC/APH2.3.10.473
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.472
1ny5ADPTranscriptional regulator (NtrC family)/0.466
3nbvANPKetohexokinase/0.466
1ht2ADPATP-dependent protease ATPase subunit HslU/0.465
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.463
3hyoADPPyridoxal kinase/0.462
1g41ADPATP-dependent protease ATPase subunit HslU/0.460
3njoP2MAbscisic acid receptor PYR1/0.460
1i44ACPInsulin receptor2.7.10.10.456
2b9wFADPutative aminooxidase/0.456
4en4ATPPyridoxal kinase2.7.1.350.454
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
1kp8AGS60 kDa chaperonin/0.453
4n9wGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.452
3keuATPPyridoxal kinase2.7.1.350.451
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4ki8ADP60 kDa chaperonin/0.451
3rusADPChaperonin/0.448
4h9tHL4Phosphotriesterase/0.448
3fhyATPPyridoxal kinase2.7.1.350.447
1rfvADPPyridoxal kinase2.7.1.350.446
2bx8AZQSerum albumin/0.445
1e94ANPATP-dependent protease ATPase subunit HslU/0.444
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.444
1tllNAPNitric oxide synthase, brain1.14.13.390.443
3q4zANPSerine/threonine-protein kinase PAK 12.7.11.10.443
3srzUPGToxin A/0.442
4ekkANPRAC-alpha serine/threonine-protein kinase2.7.11.10.442
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1wc1TATAdenylate cyclase/0.441
3vthAPCCarbamoyltransferase/0.441
4fxfATPPyruvate kinase PKM2.7.1.400.441
5iqiGNPBifunctional AAC/APH2.3.10.441
2a5yATPCell death protein 4/0.440
2hw1ANPKetohexokinase/0.440
3hu1AGSTransitional endoplasmic reticulum ATPase3.6.4.60.440
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.440