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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1yw9A84Methionine aminopeptidase 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1yw9A84Methionine aminopeptidase 2/1.000
2ea2F77Methionine aminopeptidase 2/0.734
2ea4F79Methionine aminopeptidase 2/0.732
1yw7A41Methionine aminopeptidase 2/0.694
2ga2A19Methionine aminopeptidase 2/0.669
1yw8A75Methionine aminopeptidase 2/0.650
1r5hAO2Methionine aminopeptidase 2/0.624
1r58AO5Methionine aminopeptidase 2/0.607
1r5gAO1Methionine aminopeptidase 2/0.607
2oazI96Methionine aminopeptidase 2/0.600
1qzyTDEMethionine aminopeptidase 2/0.534
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
1c7oPPGHemolysin/0.449
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
2xuqTZ4Acetylcholinesterase3.1.1.70.442
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440