Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1vgrCOAFormyl-CoA:oxalate CoA-transferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1vgrCOAFormyl-CoA:oxalate CoA-transferase/1.000
2vjmCOAFormyl-CoA:oxalate CoA-transferase/0.547
1vgqCAOFormyl-CoA:oxalate CoA-transferase/0.523
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.522
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.511
1xp8AGSProtein RecA/0.480
1obnASVIsopenicillin N synthase1.21.3.10.465
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.464
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.464
1ftlDNQGlutamate receptor 2/0.463
3jzdNADMaleylacetate reductase/0.461
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
1f20FADNitric oxide synthase, brain1.14.13.390.459
3zkyWT4Isopenicillin N synthase1.21.3.10.459
4bfvZVVPantothenate kinase2.7.1.330.457
4h6pFMNChromate reductase/0.457
2i7nACOPantothenate kinase 12.7.1.330.456
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.454
3otwCOAPhosphopantetheine adenylyltransferase/0.454
3ixp834Ecdysone receptor/0.453
1icpFMN12-oxophytodienoate reductase 11.3.1.420.451
3p62FMNPentaerythritol tetranitrate reductase/0.451
4du82P0Mevalonate diphosphate decarboxylase/0.451
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.451
3khuUPGUDP-glucose 6-dehydrogenase1.1.1.220.450
1xmmM7Gm7GpppX diphosphatase3.6.1.590.449
3f03FMNPentaerythritol tetranitrate reductase/0.449
4bmsNAPAlclohol dehydrogenase/short-chain dehydrogenase/0.449
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.449
5jlaNADPutative short-chain dehydrogenase/reductase/0.449
1eiiRTLRetinol-binding protein 2/0.448
1icsFMN12-oxophytodienoate reductase 11.3.1.420.448
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
2vbdV10Isopenicillin N synthase1.21.3.10.448
4qaiFMNNADPH dehydrogenase/0.448
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.448
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.447
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.446
2y60M8FIsopenicillin N synthase1.21.3.10.446
1h50FMNPentaerythritol tetranitrate reductase/0.445
2zrjAGSProtein RecA/0.445
3q1fYPPBeta-lactamase/0.445
1qiqACCIsopenicillin N synthase1.21.3.10.444
1xddAAYIntegrin alpha-L/0.444
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.444
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.444
4zrnUPGUDP-glucose 4-epimerase, putative/0.444
1hb1OCVIsopenicillin N synthase1.21.3.10.443
3f3sNADLambda-crystallin homolog/0.443
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.443
4locBTNPyruvate carboxylase/0.443
1vyrFMNPentaerythritol tetranitrate reductase/0.442
2iviACWIsopenicillin N synthase1.21.3.10.442
2jb4A14Isopenicillin N synthase1.21.3.10.442
3qwbNDPProbable quinone oxidoreductase1.6.5.50.442
4qxr1YEStimulator of interferon genes protein/0.442
5dp2NAPCurF/0.442
1lb9DNQGlutamate receptor 2/0.440
1thyUMPThymidylate synthase/0.440
3t8oATPRhodopsin kinase/0.440
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.440