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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1r5gAO1Methionine aminopeptidase 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1r5gAO1Methionine aminopeptidase 2/1.000
1qzyTDEMethionine aminopeptidase 2/0.680
1r5hAO2Methionine aminopeptidase 2/0.639
1yw8A75Methionine aminopeptidase 2/0.633
1r58AO5Methionine aminopeptidase 2/0.594
2ga2A19Methionine aminopeptidase 2/0.573
1yw7A41Methionine aminopeptidase 2/0.563
1yw9A84Methionine aminopeptidase 2/0.553
2ea2F77Methionine aminopeptidase 2/0.549
2oazI96Methionine aminopeptidase 2/0.529
2ea4F79Methionine aminopeptidase 2/0.500
3pkbY16Methionine aminopeptidase 2/0.485
3pkdY10Methionine aminopeptidase 2/0.484
3pkaY02Methionine aminopeptidase 2/0.481
3pkeY10Methionine aminopeptidase 2/0.476
3iu7FCDMethionine aminopeptidase 2/0.470
2evcFC3Methionine aminopeptidase/0.466
2xuhTZ4Acetylcholinesterase3.1.1.70.457
2q94A04Methionine aminopeptidase/0.456
4flkY10Methionine aminopeptidase 1/0.456
4fllYZ6Methionine aminopeptidase 1/0.447
2g6pHM2Methionine aminopeptidase 1/0.446
4bfzZVZPantothenate kinase2.7.1.330.444
2xuqTZ4Acetylcholinesterase3.1.1.70.443