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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1qzyTDEMethionine aminopeptidase 2

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1qzyTDEMethionine aminopeptidase 2/1.000
1r5gAO1Methionine aminopeptidase 2/0.636
1r5hAO2Methionine aminopeptidase 2/0.621
2oazI96Methionine aminopeptidase 2/0.585
1r58AO5Methionine aminopeptidase 2/0.543
2ea2F77Methionine aminopeptidase 2/0.508
1yw7A41Methionine aminopeptidase 2/0.482
1yw9A84Methionine aminopeptidase 2/0.465
2ga2A19Methionine aminopeptidase 2/0.464
1yw8A75Methionine aminopeptidase 2/0.458
3ufl508Beta-secretase 13.4.23.460.458
3pkeY10Methionine aminopeptidase 2/0.451
2xuqTZ4Acetylcholinesterase3.1.1.70.449
3qe2FMNNADPH--cytochrome P450 reductase/0.443