sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 1.000 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.624 | |
| 2yaa | ATP | Death-associated protein kinase 2 | / | 0.478 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.477 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.476 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.465 | |
| 4agu | D15 | Cyclin-dependent kinase-like 1 | / | 0.462 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.458 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.457 | |
| 4ifc | ADP | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.456 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.451 | |
| 4fg7 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.451 | |
| 3beg | ANP | SRSF protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 5av3 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.443 | |
| 4gv1 | 0XZ | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.443 | |
| 5av2 | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 4h3q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 |